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Filtered Search Results
Medchemexpress LLC Pomalidomide-C3-adavosertib | 2414418-49-6 | MFCD11593005 | 99.8% | 799.88 | C42H45N11O6 | 5 MG
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Pomalidomide-C3-adavosertib is a proteolysis targeting chimera (PROTAC) that drives CRBN-mediated degradation of the Wee1 kinase, producing rapid target knockdown and downstream antiproliferative effects in cancer cells. It induces DNA damage and apoptosis, and has utility in cellular pharmacology and mechanism-of-action studies, including combination experiments that probe synergy with DNA damage response inhibitors.
- Rapid and selective Wee1 degradation (IC50 = 3.58 nM).
- Antiproliferative activity in MOLT-4 cells (IC50 = 390 nM).
- CRBN-dependent ubiquitin-proteasome mechanism of action.
- Induces DNA damage, apoptosis, and G2/M checkpoint deregulation.
- Suitable for in vitro target validation and cellular pharmacology assays.
- Stable as a powder when stored under recommended conditions.
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eMolecules 3883-39-4 | 5-methyl-2-vinylpyridine | Abosyn Chemicals Inc. | MFCD08703184 | 119.167 | C8H9N | 0.000 | Cc1ccc(C=C)nc1 | 5g | 476139903
5-methyl-2-vinylpyridine | Abosyn Chemicals Inc. | 3883-39-4 | MFCD08703184 | 119.167 | C8H9N | 0.000 | Cc1ccc(C=C)nc1 | 5g | 476139903
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Matrix Scientific THIOPHENE-3-ACETIC ACID-5G
Thiophene-3-acetic acid, 98%; 5g,C6H6O2S, MFCD00005473, mw 142.18, [6964-21-2]
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eMolecules 1057855-79-4 | 1,6-Naphthyridine-2-carboxylic acid, 5,6,7,8-tetrahydro-, methyl ester | Abosyn Chemicals Inc. | MFCD16987625 | 192.218 | C10H12N2O2 | 0.000 | COC(=O)c1ccc2CNCCc2n1 | 1g | 704952418
1,6-Naphthyridine-2-carboxylic acid, 5,6,7,8-tetrahydro-, methyl ester | Abosyn Chemicals Inc. | 1057855-79-4 | MFCD16987625 | 192.218 | C10H12N2O2 | 0.000 | COC(=O)c1ccc2CNCCc2n1 | 1g | 704952418
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Medchemexpress LLC Phenazine (methylsulfate) | 299-11-6 | 306.34 | 500 MG
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Phenazine methylsulfate is a free radical generator that functions as an electron transfer reactant in cell viability assays. It possesses insecticidal properties and induces oxidative DNA damage and cell apoptosis, demonstrating antitumor activity.
- Stimulates proton transport by promoting photosynthetic electron flow.
- Disrupts and clears Leishmania amastigotes from macrophages without significant harm to host cells.
- Inhibits or kills Leishmania promastigotes.
- Induces apoptosis in A375, G361, and LOX cells.
- Leads to the upregulation of heat shock, oxidative, and genotoxic stress response gene expression in A375 cells.
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eMolecules 3663-61-4 | 5-(2-Furyl)-4h-1,2,4-triazol-3-amine | MFCD07427745 | 1g
Ambeed | (3-((45-Dihydrothiazol-2-yl)carbamoyl)phenyl)boronic acid | 250mg | 721602093 | A216496 | 871333-06-1 | MFCD07363799 | 250.080 | C10H11BN2O3S
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eMolecules Building Block Tool<|a>
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STA Pharmaceutical 2'-F U amidite | 5 g | CAS 146954-75-8 | MDL MFCD11113919
2'-F U amidite is a Amidite reagent (Subcategory: 2'-F Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 146954-75-8
- MDL: MFCD11113919
- InChIKey: HQHQPAYRJJMYQX-DJTPZYMWSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥99%
- Container Type: 250 mL Glass (28-400)
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 174.7 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: COC1=CC=C(C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@H]4O[C@@H](N5C=CC(NC5=O)=O)[C@@H]([C@@H]4OP(N(C(C)C)C(C)C)OCCC#N)F)C=C1
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eMolecules 288-32-4 | 1H-Imidazole | AA Blocks LLC | MFCD00005183 | 68.079 | C3H4N2 | 0.000 | c1c[nH]cn1 | 5g | 532064558
1H-Imidazole | AA Blocks LLC | 288-32-4 | MFCD00005183 | 68.079 | C3H4N2 | 0.000 | c1c[nH]cn1 | 5g | 532064558
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1PLUSCHEM LLC
NC3935481 3 4-DIMETHYLFURAN
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eMolecules 1199773-46-0 | N-(Furan-2-ylmethyl) 4-(4-bromopyrazol-1-yl)benzenesulfonamide | Combi-Blocks | MFCD13195743 | 382.230 | C14H12BrN3O3S | 97.000 | Brc1cnn(c1)-c1ccc(cc1)S(=O)(=O)NCc1ccco1 | 1g | 117543103
N-(Furan-2-ylmethyl) 4-(4-bromopyrazol-1-yl)benzenesulfonamide | Combi-Blocks | 1199773-46-0 | MFCD13195743 | 382.230 | C14H12BrN3O3S | 97.000 | Brc1cnn(c1)-c1ccc(cc1)S(=O)(=O)NCc1ccco1 | 1g | 117543103
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Medchemexpress LLC 1H-Pyrrolo[2,3-b]pyridine 7-oxide | 55052-24-9 | >99.1% | C7H6N2O | 50 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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1H-Pyrrolo[2,3-b]pyridine 7-oxide is a drug intermediate used for the synthesis of various active compounds. It is for research use only and not sold to patients.
- Drug intermediate for the synthesis of various active compounds.
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Medchemexpress LLC 3- 2-THIENYL -D-ALAN 5G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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3- 2-THIENYL -D-ALAN 5G
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Medchemexpress LLC 3- 2-THIENYL -D-ALAN 1G
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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3- 2-THIENYL -D-ALAN 1G
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Medchemexpress LLC (R)-3-(Boc-amino)pyrrolidine | 122536-77-0 | 186.25 | 5 G
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tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent suitable for life science research. It serves as an intermediate in organic synthesis and as a pharmaceutical intermediate.
- Used as a biochemical reagent
- Suitable for life science research
- Functions as an intermediate in organic synthesis
- Serves as a pharmaceutical intermediate
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Medchemexpress LLC Complement C3 Mouse 50ug | 50ug
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Complement C3 protein activates the complement system playing a central role in both classical and alternative pathways C3b binds covalently to cell surface carbohydrates or immune aggregates while C3a acts as an inflammatory mediator inducing neutrophil chemoattraction and promoting smooth muscle contraction increased vascular permeability and histamine release The shorter isoform of C3a stimulates B-cells Complement C3 Protein Mouse (HEK293 His) is the recombinant mouse-derived Complement C3 protein expressed by HEK293 with C-His labeled tag
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